Growth failure in hereditary spherocytosis and the effect of splenectomy

Abstract

                <span> 
                  </span><h3>Objectives</h3> 
                  <p>To analyze growth-failure and improvement, if any, following splenectomy in children with hereditary spherocytosis.</p> 

                <span> 
                  </span><h3>Methods</h3> 
                  <p>Data collection from case-records (n=82) over 27-years (1985-2011).</p> 

                <span> 
                  </span><h3>Results</h3> 
                  <p>Prevalence of stunting was 26%; 32% were underweight. Stunted children were older in age (<em>P</em>=0.006) and presented late (<em>P</em>=0.003). Splenectomy (<em>n</em>=26) improved anemia (<em>P</em>&lt;0.001). However, height-for-age did not improve at 1-year, or 4.5-years (median) following splenectomy (<em>P</em>=1.0). Number of underweight children did not reduce at 1-<em>(P</em>=0.21), or 4.5-years (<em>P</em>=0.21) following surgery.</p> 

                <span> 
                  </span><h3>Conclusion</h3> 
                  <p>Growth-failure is frequent in children with hereditary spherocytosis in India. Splenectomy corrected the anemia but failed to improve the growth.</p> 
                <br /><br />

from # & – All via ola Kala on Inoreader http://ift.tt/2fCvKN1

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s