GATA3 as a valuable marker to distinguish clear cell papillary renal cell carcinomas from morphologic mimics

Clear cell papillary renal cell carcinoma (CCPRCC) is a low-grade, indolent neoplasm, with no reported cases of death from disease or metastasis. These lesions can show clinical, morphologic and immunophenotypic overlap with several aggressive forms of renal cell carcinoma (RCC), including clear cell (CCRCC), translocation RCC and papillary RCC (PRCC) with cytoplasmic clearing. Given the difference in behavior, it is important to reliably separate these entities.We retrospectively reviewed 47 tumors from 45 patients with morphologic features of CCPRCC.

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